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Agoura Hills, California, is an affluent bedroom community 30 miles northwest of central Los Angeles, marked by lush valleys and broad canyons.

Laboratory buildings are often the graveyard of architects' good intentions, as stringent technical requirements leave little room for environmental and aesthetic concerns.

Working out of an office in Boston's financial district — inaccessible to the public and incapable of holding large public functions — the Boston Society of Architects (BSA) wanted a change of scene.

With more than $33 billion in its asset trust endowment, the Gates Foundation is the wealthiest charitable entity in the world. But it wanted to send the right message with the architecture of its new home: bold but not arrogant, global but also a good neighbor.