In the late 1960s, Dr. Michael DeBakey performed some of the country’s first heart transplants at the Methodist Hospital in Houston.

A four-level, 46,500-square-foot cultural center in downtown Charlotte. Situated on a narrow 50-by-400-foot tract, the project includes galleries, classrooms, offices, and event space.

Steven Holl made his first sketches for the Knut Hamsun Center, in the municipality of Hamarøy, Norway, in 1994.

A single-story, 3,600-square-foot art gallery with offices, two galleries, a private viewing room, a preparator's area, and a flower garden that can accommodate sculptures.

For the hordes of tourists stuck in lines for the Colosseum or queuing up to enter the Sistine Chapel, Rome’s 2,000-year history acts as a powerful magnet.

A 1,700-square-foot museum devoted to pioneer neurosurgeon Dr. Harvey Cushing, located in a sub-basement of the Harvey Cushing/John Hay Whitney Medical Library at the Yale School of Medicine.

A 5,490-square-foot museum devoted to water and its history in Lanjarón, a Granada spa town on the southern end of the Sierra Nevada.

Francisco “Patxi” Mangado, the 54-year-old Spanish architect, compares his bronze-clad Archaeological Museum of Álava in Vitoria, Spain, to a “coffer guarding a treasure.”

A three-level, 6,000-square-foot center for the Aurora Historical Society, located in the city's downtown historic district.