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Shigeru Ban transports his unique Japanese sensibility to a Chelsea condominium with High Line views.

A 23-story, 130,000-square-foot condominium tower on the Hudson River, next to Frank Gehry's IAC building.

You can park your car right outside your apartment door in an Annabelle Selldorf–Designed 19-story tower.

In a sunlit lab filled with genotyping equipment, Dr. Christof von Kalle and colleagues at the National Center for Tumor Diseases (NCT) plumb the secrets of cellular mechanisms that create cancers.

Owner: Intrepid Fallen Heroes Fund Completion Date: June 2010 Program: A two-story, 72,000-square-foot facility for traumatic brain injury (TBI) patients at Bethesda's National Naval Medical Center. The project includes clinics; imaging facilities; spaces for physical therapy, outdoor rehabilitation, and virtual-reality-assisted rehab; offices; an auditorium; a patient lounge and coffee bar; and a skylit multipurpose space that can host activities ranging from group exercises to theater performances. Design concept and solution:The architects needed to accommodate a wide variety of programs under one roof, while creating flexible spaces that can adapt to the center's evolving needs as new findings about TBI emerge.

Owner: University of California, San Francisco Completion Date: December 2010 Program: A five-story, 56,604-square-foot medical office building on the UCSF Mount Zion hospital campus, with doctors' offices, exam rooms, staff lounges, yoga studios, spaces for education and research, and an accessible green roof with a Japanese healing garden. The building is divided between two tenants. The UCSF Medical Center, which provides outpatient services for the hospital, occupies levels 1 and 2. The Osher Center for Integrative Medicine, whose offerings include acupuncture and Ayurvedic medicine, is on floors 4 and 5, and the two offices split level 3. Design concept and

A 10-story, 467,000-square-foot outpatient cancer center with spaces for radiation and medical oncology, a laboratory, a pharmacy, a restaurant, a coffee shop, a gift shop, and physician offices.

Owner: Chickasaw Nation Health System Completion Date: July 2010 Program: A three-story, 370,425-square-foot medical center combining a hospital, outpatient clinics, and an emergency department. Located on a 230-acre plot outside of Ada, the project replaces the Chickasaw Nation's former hospital there, which the community had outgrown. The new center includes a surgical suite with four operating rooms; a diagnostic imaging department; outpatient clinics for pediatrics, behavioral health, cardiology, and other specialties; a pharmacy; and a chapel. Design concept and solution: In designing the largest public facility supported by the Chickasaw government, the architects were charged with treating the hospital as

A five-level, 150,000-square-foot outpatient cancer center belonging to the University of Virginia's (UVA) health-care system.

Owner: Hoag Hospital Completion Date: August 2010 Program: A 244,000-square-foot acute care and orthopedic specialty hospital composed of a five-story patient bed tower that adjoins a three-level central atrium. The project is a renovation of the Irvine Regional Hospital and Medical Center, a 20-year-old community hospital that was taken over by the Hoag system. A new program, the Hoag Orthopedic Institute, has nine operating rooms on the second floor of the atrium building; it replaces a mother-baby facility, which was absorbed by Hoag Hospital Newport. The Irvine project also includes two additional operating rooms, an 11-bay emergency department, imaging and